Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 10/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.46 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2448800 | 1.00 | HCRTR1 (0.46) | HCRTR1HCRTR2FPR1FPR2SLC6A4 | |
| SCHEMBL2447671 | 0.91 | HCRTR1 (0.48) | HCRTR1HCRTR2TSHRRECQLMEN1 | |
| SCHEMBL2447675 | 0.91 | HCRTR1 (0.48) | HCRTR1HCRTR2TSHRRECQLMEN1 | |
| SCHEMBL3415826 | 0.88 | HCRTR1 (0.44) | HCRTR1HCRTR2FPR1FPR2SLC6A4 | |
| SCHEMBL2925286 | 0.88 | HCRTR1 (0.44) | HCRTR1HCRTR2FPR1FPR2SLC6A4 | |
| SCHEMBL2448801 | 0.85 | HCRTR1 (0.50) | HCRTR1HCRTR2SLC6A4SLC6A3CDK4 | |
| SCHEMBL2448750 | 0.83 | HCRTR2 (0.41) | HCRTR1HCRTR2FPR1FPR2SLC6A4 | |
| SCHEMBL2448753 | 0.83 | HCRTR2 (0.41) | HCRTR1HCRTR2FPR1FPR2SLC6A4 | |
| SCHEMBL2445623 | 0.82 | HCRTR1 (0.42) | HCRTR1HCRTR2CDK4CCND1MEN1 | |
| SCHEMBL2445621 | 0.82 | HCRTR1 (0.42) | HCRTR1HCRTR2CDK4CCND1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164847-B1 | 3-AZA-BICYCLO[3.3.0]OCTANE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-09-14 | — | — | EP | claimed |