Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 5/20 | 0.37 |
| ▸ | GAK | O14976 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29577707 | 0.95 | TTK (0.38) | TTKGAKLRRK2 | |
| SCHEMBL21240264 | 0.95 | TTK (0.38) | TTKGAKLRRK2 | |
| SCHEMBL20331980 | 0.92 | TTK (0.37) | TTKGAKLRRK2 | |
| SCHEMBL24488213 | 0.86 | GAK (0.33) | TTKGAK | |
| SCHEMBL21252449 | 0.83 | TTK (0.38) | TTKGAKLRRK2 | |
| SCHEMBL21252133 | 0.82 | TTK (0.33) | TTK | |
| SCHEMBL20331964 | 0.82 | PDE10A (0.36) | TTK | |
| SCHEMBL29578107 | 0.82 | PDE10A (0.36) | TTK | |
| SCHEMBL21240243 | 0.80 | TTK (0.38) | TTK | |
| SCHEMBL21240427 | 0.80 | SUV39H2 (0.36) | TTKGAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524603-B1 | FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | ABBISKO THERAPEUTICS CO LTD (CN) | 2022-06-08 | — | — | EP | disclosed |