Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 2/20 | 0.51 |
| ▸ | FYN | P06241 | 7/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17144935 | 0.94 | KDM4E (0.53) | KITKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2448017 | 0.92 | FYN (0.53) | KITBRD4FYNCHEK2GAK | |
| SCHEMBL14974281 | 0.90 | PDGFRB (0.58) | KITKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9971233 | 0.89 | FYN (0.52) | KITBRD4FYNCHEK2GAK | |
| SCHEMBL502835 | 0.86 | FYN (0.56) | KDM4EALDH1A1SMN1; SMN2MEN1HPGD | |
| SCHEMBL13881650 | 0.84 | TSHR (0.52) | KITKDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14629856 | 0.83 | FYN (0.52) | KITKDM4EALDH1A1SMN1; SMN2FYN | |
| SCHEMBL502772 | 0.83 | FYN (0.47) | KITBRD4FYNCHEK2GAK | |
| SCHEMBL9968588 | 0.83 | FYN (0.47) | KITKDM4EALDH1A1HPGDBRD4 | |
| SCHEMBL9968558 | 0.82 | BRD4 (0.47) | KITBRD4FYNMAP3K11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130137869-A1 | LUMINOPHORES | UNIVERSITY OF YORK (UK) | 2013-05-30 | — | — | US | disclosed |
| EP-2547748-A1 | LUMINOPHORES | University of York (GB) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011114095-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2011-09-22 | — | — | WO | disclosed |