Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | FYN | P06241 | 10/20 | 0.46 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9971233 | 0.92 | FYN (0.52) | BRD4FYNKITHSD17B1HSD17B2 | |
| SCHEMBL9968588 | 0.88 | FYN (0.47) | BRD4FYNKITHSD17B1HSD17B2 | |
| SCHEMBL13881650 | 0.86 | TSHR (0.52) | BRD4FYNKITKDM1AHSD17B1 | |
| SCHEMBL9968557 | 0.86 | HSD17B1 (0.54) | KDM1AHSD17B1HSD17B2 | |
| SCHEMBL502835 | 0.83 | FYN (0.56) | BRD4FYNMAP3K11 | |
| SCHEMBL2448017 | 0.83 | FYN (0.53) | BRD4FYNKITMAP3K11TGFBR1 | |
| SCHEMBL502772 | 0.83 | FYN (0.47) | BRD4FYNKITHSD17B1HSD17B2 | |
| SCHEMBL2448859 | 0.82 | KIT (0.58) | BRD4FYNKITMAP3K11 | |
| SCHEMBL9968554 | 0.77 | KDM4E (0.43) | BRD4FYNMAP3K11BMPR1ATGFBR1 | |
| SCHEMBL17144935 | 0.76 | KDM4E (0.53) | BRD4FYNKITTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293898-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-10-23 | — | — | US | disclosed |
| US-20120157681-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157681-A1 | LUMINOPHORES | PPOX, CRY1, MPO | BRD4 1486/4885FYN 4580/4885KIT 1975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.