Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.72 |
| ▸ | DRD3 | P35462 | 4/20 | 0.60 |
| ▸ | HTR6 | P50406 | 5/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | QDPR | P09417 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24612002 | 0.87 | DRD2 (0.66) | DRD2SIGMAR1DRD3HTR6HTR2C | |
| SCHEMBL18408681 | 0.86 | DRD2 (0.67) | DRD2SIGMAR1DRD3HTR6HRH3 | |
| SCHEMBL15450839 | 0.86 | DRD2 (0.67) | DRD2SIGMAR1DRD3HTR6HRH3 | |
| Pridopidine SCHEMBL29664816 | 0.84 | DRD2 (1.00) | DRD2SIGMAR1DRD3HTR6 | |
| Pridopidine SCHEMBL166748 | 0.84 | DRD2 (1.00) | DRD2SIGMAR1DRD3HTR6 | |
| SCHEMBL4828684 | 0.84 | DRD2 (0.64) | DRD2SIGMAR1DRD3HTR6HRH3 | |
| SCHEMBL4824639 | 0.84 | DRD2 (0.80) | DRD2SIGMAR1DRD3HTR6HRH3 | |
| SCHEMBL22458966 | 0.84 | DRD2 (0.64) | DRD2SIGMAR1DRD3HTR6HRH3 | |
| SCHEMBL10181371 | 0.83 | DRD2 (0.62) | DRD2SIGMAR1DRD3HTR6 | |
| Pridopidine SCHEMBL15007479 | 0.83 | DRD2 (0.97) | DRD2SIGMAR1DRD3HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325443-B1 | PROCESS FOR PREPARING PRIDOPIDINE | Prilenia Neurotherapeutics Ltd (IL) | 2022-06-08 | — | — | EP | disclosed |