⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23651598 | 0.85 | GBA1 (0.31) | — | |
| SCHEMBL21191571 | 0.81 | KCNH2 (0.38) | — | |
| SCHEMBL172022 | 0.81 | — | — | |
| SCHEMBL21191622 | 0.78 | HTR2A (0.33) | — | |
| SCHEMBL19661595 | 0.75 | — | — | |
| SCHEMBL24071293 | 0.75 | — | — | |
| SCHEMBL20012662 | 0.75 | GNAO1 (0.34) | — | |
| SCHEMBL20350217 | 0.74 | CYP1A2 (0.37) | — | |
| SCHEMBL8284747 | 0.74 | — | — | |
| SCHEMBL23183916 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239937-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118239938-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2024-06-25 | — | — | CN | disclosed |
| US-20220175735-A1 | METHODS OF TREATING PULMONARY DISEASES AND DISORDERS | PROTEOSTASIS THERAPEUTICS INC (US) | 2022-06-09 | — | — | US | disclosed |