Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24490102 | 0.87 | KIF11 (0.52) | KIF11SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL24490106 | 0.87 | KIF11 (0.52) | KIF11SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL11792580 | 0.82 | SLC6A4 (0.76) | SLC6A4HRH3SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL11803430 | 0.81 | SLC6A4 (0.74) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL6716414 | 0.79 | ESR1 (0.67) | KIF11SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL24490209 | 0.76 | SLC6A4 (0.69) | KIF11SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL24490097 | 0.75 | SLC6A4 (0.62) | KIF11SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL24490020 | 0.75 | SLC6A4 (0.62) | KIF11SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL1248114 | 0.75 | SLC6A4 (0.58) | SLC6A4HRH3SLC6A2SLC6A3CA1 | |
| SCHEMBL1120034 | 0.74 | KIF11 (0.58) | KIF11SLC6A4HRH3SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177488-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | CIT THERAPEUTICS LLC | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177488-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | SUMO1, SUMO2, SUMO3 | KIF11 3058/4885SLC6A4 4468/4885HRH3 4315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.