Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22460949 | 0.91 | KIF11 (0.37) | KIF11ALDH1A1MAPTACHECCR2 | |
| SCHEMBL22460902 | 0.91 | KIF11 (0.53) | KIF11GID4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22460919 | 0.91 | KIF11 (0.53) | KIF11GID4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24490161 | 0.89 | ESR1 (0.44) | ALDH1A1MAPTACHESLC6A2SLC6A4 | |
| SCHEMBL24490371 | 0.87 | KIF11 (0.48) | KIF11MAPT | |
| SCHEMBL24490097 | 0.82 | SLC6A4 (0.62) | KIF11SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24490020 | 0.82 | SLC6A4 (0.62) | KIF11SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24490249 | 0.81 | KIF11 (0.41) | KIF11GID4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24490248 | 0.81 | KIF11 (0.41) | KIF11GID4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24490268 | 0.81 | NPC1 (0.42) | ALDH1A1MAPTACHECCR2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177488-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | CIT THERAPEUTICS LLC | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177488-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | SUMO1, SUMO2, SUMO3 | KIF11 3058/4885ALDH1A1 1950/4885MAPT 2442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.