SCHEMBL24490488

SCHEMBL24490488

CCCCC1(CCCC)c2ccccc2-c2ccc(C(=O)/C(CC3CCCCC3)=N/OC(=O)c3cccc(CCCC4(CCC)c5ccccc5-c5ccc(C(=O)/C(CC6CCCCC6)=N/OC(=O)c6ccccc6)cc54)c3)cc21

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PPM1D O15297 2/20 0.34
▸ CCR5 P51681 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ PPARG P37231 1/20 0.31
▸ PPARA Q07869 1/20 0.31
▸ REN P00797 1/20 0.31
▸ CYP4F2 P78329 1/20 0.30
▸ CYP4A11 Q02928 1/20 0.30
▸ PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24497048 0.92 POLB (0.35) POLBPDK2
SCHEMBL24497049 0.90 POLB (0.36) POLBPDK2
SCHEMBL24490466 0.89 PDK2 (0.36) POLBPDK2
SCHEMBL25711214 0.89 POLB (0.34) POLBPDK2
SCHEMBL22355421 0.84 PDK2 (0.36) POLBPDK2
SCHEMBL24490489 0.84 POLB (0.37) POLBPDK2
SCHEMBL24490437 0.83 PDK2 (0.36) POLBPDK2
SCHEMBL18123001 0.82 PDK2 (0.37) POLBPDK2
SCHEMBL22355444 0.81 POLB (0.37) POLBPDK2
SCHEMBL18122990 0.81 PDK2 (0.37) POLBPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242692-A1 COMPOSITION AND CURED PRODUCT TOKYO OHKA KOGYO CO., LTD. (JP) 2023-08-03 — — US disclosed
US-20220177641-A1 CURABLE COMPOSITION, CURED PRODUCT, AND COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2022-06-09 — — US disclosed
US-20220177673-A1 CURABLE COMPOSITION, CURED PRODUCT, AND COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2022-06-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220177641-A1 CURABLE COMPOSITION, CURED PRODUCT, AND COMPOUND CROCC, RCSD1, WDR5 PPM1D 3326/4885CCR5 4368/4885POLB 1946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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