Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24492026 | 1.00 | NR1H2 (0.53) | NR1H2DPP4USP2SMN1; SMN2NAMPT | |
| SCHEMBL29290591 | 0.88 | DPP4 (0.52) | NR1H2DPP4USP2SMN1; SMN2MEN1 | |
| SCHEMBL29290580 | 0.88 | DPP4 (0.52) | NR1H2DPP4USP2SMN1; SMN2MEN1 | |
| SCHEMBL29290578 | 0.88 | DPP4 (0.52) | NR1H2DPP4USP2SMN1; SMN2MEN1 | |
| SCHEMBL24491836 | 0.88 | DPP4 (0.52) | NR1H2DPP4USP2SMN1; SMN2MEN1 | |
| SCHEMBL24491991 | 0.88 | DPP4 (0.52) | NR1H2DPP4USP2SMN1; SMN2MEN1 | |
| SCHEMBL24491945 | 0.88 | DPP4 (0.52) | NR1H2DPP4USP2SMN1; SMN2MEN1 | |
| SCHEMBL24491997 | 0.88 | DPP4 (0.52) | NR1H2DPP4USP2SMN1; SMN2MEN1 | |
| SCHEMBL29940743 | 0.87 | NR1H2 (0.49) | NR1H2DPP4USP2SMN1; SMN2NAMPT | |
| SCHEMBL24491907 | 0.86 | MEN1 (0.50) | NR1H2DPP4MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177508-A1 | C10-Cyclic Substituted 13-Membered Macrolides and Uses Thereof | ZIKANI THERAPEUTICS, INC. | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177508-A1 | C10-Cyclic Substituted 13-Membered Macrolides and Uses Thereof | RPS14, RPL12, RPL13A | NR1H2 657/4885DPP4 1443/4885USP2 3106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.