RPL12

Large ribosomal subunit protein uL11 · P30050 · RPL12 on Sugi Atlas →

3,676 patent compounds predicted against RPL12, 1,926 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL5500526	0.41	4/20
SCHEMBL5500532	0.41	4/20
SCHEMBL5503310	0.41	4/20
SCHEMBL11844361	0.35	4/20
SCHEMBL2000440	0.39	3/20
SCHEMBL8219903	0.36	3/20
SCHEMBL11627320	0.34	3/20
SCHEMBL10271044	0.55	2/20
SCHEMBL6394396	0.47	2/20
N-Methylpiperidine (SCHEMBL11205373)	0.42	2/20
Bicarbonate (SCHEMBL9058396)	0.42	2/20
SCHEMBL4960293	0.41	2/20
SCHEMBL4961968	0.40	2/20
SCHEMBL6686992	0.40	2/20
SCHEMBL9429122	0.38	2/20
Chloramphenicol (SCHEMBL10796001)	1.00	1/20
Geneticin (SCHEMBL15596)	0.93	1/20
Geneticin (SCHEMBL5006573)	0.93	1/20
Geneticin (SCHEMBL9920496)	0.93	1/20
Chloramphenicol (SCHEMBL16111)	0.90	1/20

Clinical trials — most relevant to RPL12 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Topical Metformin Emulgel VS Salicylic Acid Peeling in Treatment of Acne Vulgaris	PHASE4	UNKNOWN
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes	PHASE4	UNKNOWN
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients	PHASE2	COMPLETED
A Study on the Tolerability and Early Efficacy of hLF1-11 in Patients With Proven Candidaemia	PHASE1/PHASE2	WITHDRAWN
Everolimus for Children With Recurrent or Progressive Ependymoma	PHASE2	COMPLETED
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients	PHASE1/PHASE2	COMPLETED
EBV Lytic Reactivation Therapy Combined With PD-1 Antibody in Recurrent/Metastatic Nasopharyngeal Carcinoma	PHASE2	NOT_YET_RECRUITING
Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors	PHASE2	RECRUITING
Targeting Endoplasmic Reticulum Stress in Human Hypertension	PHASE1/PHASE2	RECRUITING
Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Gastric Cancer	PHASE1/PHASE2	COMPLETED
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma	PHASE2	COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Gastric Cancer	PHASE1	COMPLETED
Phase I Safety and Immunogenicity Preventative Vaccine Trial Based on Recombinant Tat Protein	PHASE1	COMPLETED
Cixutumumab and Temsirolimus in Treating Younger Patients With Solid Tumors That Have Recurred or Not Responded to Treatment	PHASE1	COMPLETED
Cytomegalovirus (CMV) MicroRNA Expression in Vivo and Immune Evasion Correlates	nan	COMPLETED
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
Mitoquines in COPD	nan	UNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML)	nan	COMPLETED
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Torisel in Addition to Standard Chemotherapy With Radiation for Advanced Head and Neck Cancer	nan	WITHDRAWN
Effect of Branched Chain Amino Acids on Muscle	nan	COMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
Longitudinal Study of the Porphyrias	nan	RECRUITING
Mobilization of CD34+ Peripheral Blood Stem Cells in Patients With Diamond Blackfan Anemia Syndrome (DBAS)	nan	RECRUITING
miR-155 Expression in Episodic and Chronic Migraine	nan	UNKNOWN
Role of Sorcin and Annexin A3 in Breast Cancer Patients	nan	UNKNOWN
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Clinical Study of Muenke Syndrome (FGFR3-Related Craniosynostosis)	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a RPL12 binder may also engage these)

Protein	Name	Similarity
G1SMR7	—	1.000	G1SMR7 →
P23358	—	1.000	P23358 →
Q6QMZ7	—	1.000	Q6QMZ7 →
P35979	—	1.000	P35979 →
P61284	—	1.000	P61284 →
E2RR58	—	1.000	E2RR58 →
P61865	—	1.000	P61865 →
P0CX53	—	1.000	P0CX53 →
P61866	—	1.000	P61866 →
Q54J50	—	1.000	Q54J50 →
Q9FF52	—	1.000	Q9FF52 →
P0CX54	—	1.000	P0CX54 →
Q5AJF7	—	1.000	Q5AJF7 →
P50884	—	1.000	P50884 →
O50003	—	1.000	O50003 →
Q9C285	—	1.000	Q9C285 →
Q8SR84	—	1.000	Q8SR84 →
P50883	—	1.000	P50883 →
Q9LFH5	—	1.000	Q9LFH5 →
P0CT83	—	1.000	P0CT83 →
P0CT84	—	1.000	P0CT84 →
Q8EX25	—	0.992	Q8EX25 →
Q0W049	—	0.990	Q0W049 →
Q971J0	—	0.990	Q971J0 →
P35025	—	0.990	P35025 →
P53875	—	0.990	P53875 →
Q5XIE3	—	0.990	Q5XIE3 →
C3N7D9	—	0.989	C3N7D9 →
Q6L1Y0	—	0.989	Q6L1Y0 →
B3PM28	—	0.989	B3PM28 →