Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.68 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 6/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 5/20 | 0.41 |
| ▸ | FLT3 | P36888 | 5/20 | 0.41 |
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | MET | P08581 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092812 | 0.81 | KEAP1 (1.00) | KEAP1DYRK1AMEN1CYP1A2KMT2A | |
| SCHEMBL74518 | 0.81 | KEAP1 (0.68) | KEAP1DYRK1AMEN1CYP1A2KMT2A | |
| SCHEMBL2049672 | 0.81 | KEAP1 (0.68) | KEAP1DYRK1AMEN1CYP1A2KMT2A | |
| SCHEMBL14638413 | 0.81 | KEAP1 (0.68) | KEAP1DYRK1AMEN1CYP1A2KMT2A | |
| SCHEMBL2535366 | 0.81 | KEAP1 (0.68) | KEAP1DYRK1AMEN1CYP1A2KMT2A | |
| SCHEMBL14554770 | 0.81 | KEAP1 (0.68) | KEAP1DYRK1AMEN1CYP1A2KMT2A | |
| Ammonia Solution, Strong SCHEMBL28922912 | 0.79 | KEAP1 (0.66) | KEAP1DYRK1AMEN1CYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL23201169 | 0.79 | KEAP1 (0.96) | KEAP1DYRK1AMEN1CYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL17184538 | 0.79 | KEAP1 (0.96) | KEAP1DYRK1AMEN1CYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL8830070 | 0.79 | KEAP1 (0.66) | KEAP1DYRK1AMEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022116998-A1 | FUSED HETEROCYCLIC DERIVATIVES AS HBV INHIBITORS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-06-09 | — | — | WO | disclosed |
| WO-2022116998-A1 | FUSED HETEROCYCLIC DERIVATIVES AS HBV INHIBITORS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-06-09 | — | — | WO | disclosed |