Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.51 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL193349 | 0.99 | ULK1 (0.55) | ULK1KMT2ARAB9ANPC1ENPP3 | |
| SCHEMBL2146675 | 0.91 | KMT2A (0.56) | ULK1KMT2ARAB9ANPC1ENPP3 | |
| SCHEMBL2146682 | 0.91 | KMT2A (0.56) | ULK1KMT2ARAB9ANPC1ENPP3 | |
| Hydrochloric Acid SCHEMBL2146071 | 0.90 | KMT2A (0.55) | ULK1KMT2ARAB9ANPC1ENPP3 | |
| Hydrochloric Acid SCHEMBL2146077 | 0.90 | KMT2A (0.55) | ULK1KMT2ARAB9ANPC1ENPP3 | |
| SCHEMBL4564743 | 0.87 | ULK1 (0.64) | ULK1KMT2ARAB9AALOX15PTPN1 | |
| SCHEMBL2448229 | 0.85 | ULK1 (0.56) | ULK1RAB9AENPP3ENPP1ENPP2 | |
| SCHEMBL2451482 | 0.85 | ULK1 (0.56) | ULK1RAB9ANPC1POLB | |
| SCHEMBL2446479 | 0.85 | HPGD (0.66) | ULK1KMT2AALOX15PTPN1POLB | |
| SCHEMBL1318166 | 0.85 | HPGD (0.66) | ULK1KMT2AALOX15PTPN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022158875-A1 | ANTIBACTERIAL PEPTIDE AND COMPOUND TARGETING KLEBSIELLA PNEUMONIAE TOXIN-ANTITOXIN SYSTEM, AND USES OF SAME | 서울대학교산학협력단 | 2022-07-28 | — | — | WO | disclosed |
| EP-2362775-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2011-09-07 | — | — | EP | disclosed |