Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | UBE2M | P61081 | 1/20 | 0.59 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10724061 | 0.84 | TSHR (0.78) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10720174 | 0.82 | TSHR (0.63) | TSHRALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL16309014 | 0.81 | TSHR (0.58) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL20116458 | 0.78 | TSHR (0.66) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL19088586 | 0.78 | HPGD (0.74) | TSHRHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL15499084 | 0.78 | HPGD (0.75) | TSHRHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL12471546 | 0.78 | TSHR (0.58) | TSHRALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3660045 | 0.78 | TSHR (0.69) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2835506 | 0.77 | TSHR (0.68) | TSHRALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL19088577 | 0.77 | HPGD (0.73) | TSHRHPGDALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022118966-A1 | AGENT FOR PROMOTING NUCLEIC ACID MOLECULE UPTAKE INTO CELLS, PHARMACEUTICAL COMPOSITION, AND NOVEL COMPOUND | 国立大学法人京都大学 | 2022-06-09 | — | — | WO | disclosed |