Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | MGLL | Q99685 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | DHFR | P00374 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10724061 | 0.92 | TSHR (0.78) | TSHRMGLLCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20116458 | 0.86 | TSHR (0.66) | TSHRMGLLCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2835506 | 0.85 | TSHR (0.68) | TSHRMGLLGAAMEN1KMT2A | |
| SCHEMBL3659481 | 0.84 | TSHR (0.76) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1299296 | 0.83 | SMN1; SMN2 (0.71) | TSHRMGLLGAAPOLBMEN1 | |
| SCHEMBL8410650 | 0.82 | TSHR (0.62) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22123601 | 0.82 | ALDH1A1 (0.55) | TSHRMGLLCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19915895 | 0.82 | MGLL (0.56) | MGLLGAAPOLBMEN1KMT2A | |
| SCHEMBL29067078 | 0.81 | MAPT (0.71) | TSHRMGLLGAAPOLBMEN1 | |
| SCHEMBL3004296 | 0.81 | SMN1; SMN2 (0.70) | MGLLGAAPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234998-B1 | SPECIFIC INHIBITORS OF PTERIDINE REDUCTASE WITH ANTIPARASITIC ACTION | TYDOCK PHARMA S R L (IT) | 2015-08-19 | — | — | EP | disclosed |
| US-20100305134-A1 | SPECIFIC INHIBITORS OF PTERIDINE REDUCTASE WITH ANTIPARASITIC ACTION | TYDOCK PHARMA S.R.L. (IT) | 2010-12-02 | — | — | US | disclosed |
| EP-2234998-A2 | SPECIFIC INHIBITORS OF PTERIDINE REDUCTASE WITH ANTIPARASITIC ACTION | Tydock Pharma S.r.l. (IT) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009080367-A2 | SPECIFIC INHIBITORS OF PTERIDINE REDUCTASE WITH ANTIPARASITIC ACTION | TYDOCKPHARMA S.R.L. (IT) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305134-A1 | SPECIFIC INHIBITORS OF PTERIDINE REDUCTASE WITH ANTIPARASITIC ACTION | QDPR, DHFR, DDC | TSHR 892/4885MGLL 3378/4885CYP1A2 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.