SCHEMBL244958

SCHEMBL244958

CN(C)c1ccc2c(c1)Sc1cc(N(C)C)ccc1N2C(=O)NCC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.59
MAPK1 P28482 2/20 0.59
MEN1 O00255 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
BCHE P06276 12/20 0.46
MAPT P10636 2/20 0.45
GAA P10253 1/20 0.45
NPSR1 Q6W5P4 2/20 0.43
SNCA P37840 1/20 0.42
ALDH1A1 P00352 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
RAB9A P51151 1/20 0.41
ACHE P22303 3/20 0.41
POLB P06746 1/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386704 1.00 KMT2A (0.59) KMT2AMAPK1MEN1TDP1L3MBTL1
SCHEMBL241699 0.99 KMT2A (0.57) KMT2AMAPK1MEN1TDP1L3MBTL1
SCHEMBL241701 0.99 KMT2A (0.57) KMT2AMAPK1MEN1TDP1L3MBTL1
SCHEMBL29686941 0.99 KMT2A (0.57) KMT2AMAPK1MEN1TDP1L3MBTL1
SCHEMBL16872264 0.99 KMT2A (0.57) KMT2AMAPK1MEN1TDP1L3MBTL1
SCHEMBL1828806 0.94 KMT2A (0.59) KMT2AMAPK1MEN1TDP1L3MBTL1
SCHEMBL9567866 0.87 MEN1 (0.56) KMT2AMAPK1MEN1TDP1L3MBTL1
SCHEMBL29387322 0.87 KMT2A (0.53) KMT2AMAPK1MEN1TDP1L3MBTL1
SCHEMBL241700 0.87 KMT2A (0.53) KMT2AMAPK1MEN1TDP1L3MBTL1
SCHEMBL29387164 0.87 KMT2A (0.53) KMT2AMAPK1MEN1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3550030-B1 METHOD FOR MEASURING GLYCATION RATE OF HEMOGLOBIN TOYO BOSEKI (JP) 2025-01-01 EP claimed
EP-3492600-B1 METHOD FOR MEASURING GLYCATED HEMOGLOBIN HITACHI CHEMICAL DIAGNOSTICS SYSTEMS CO LTD (JP) 2024-04-24 EP claimed
EP-3461908-B1 MEASUREMENT OF GLYCOPROTEIN ARKRAY INC (JP) 2023-08-30 EP claimed
US-11313863-B2 Measurement of glycoprotein ARKRAY, INC. (JP) 2022-04-26 US claimed
EP-2653506-B1 METHOD FOR PRESERVING AQUEOUS SOLUTION CONTAINING LEUCO CHROMOGEN HITACHI CHEMICAL DIAGNOSTICS SYSTEMS CO LTD (JP) 2021-12-08 EP claimed
US-11168349-B2 Method for measuring glycated hemoglobin HITACHI CHEMICAL DIAGNOSTICS SYSTEMS CO., LTD. (JP) 2021-11-09 US claimed
EP-2543706-B1 METHOD FOR STABILIZING OF COLOR DEVELOPER AND USE THEREOF ARKRAY INC (JP) 2021-05-26 EP claimed
US-20200200769-A1 METHOD FOR MEASURING GLYCATED HEMOGLOBIN HITACHI CHEMICAL DIAGNOSTICS SYSTEMS CO., LTD. (JP) 2020-06-25 US claimed
EP-3527669-B1 KIT FOR HEMOGLOBIN A1C QUANTITATIVE ANALYSIS I SENS INC (KR) 2020-04-29 EP claimed
EP-3636767-A1 METHOD FOR MEASURING GLYCATED HEMOGLOBIN Hitachi Chemical Diagnostics Systems Co., Ltd. (JP) 2020-04-15 EP claimed
EP-1726955-A1 METHOD OF STABILIZING OXIDIZABLE COLOR-ASSUMING REAGENT DAIICHI PURE CHEMICALS CO., LTD. (JP) 2006-11-29 EP claimed
US-6951728-B2 Multilayer reagent test strips to quantify glycated protein in a physiological sample LIFESCAN, INC. (US) 2005-10-04 US claimed
EP-0926244-B1 METHODS AND REAGENTS FOR QUANTITATIVELY DETERMINING ASCORBIC ACID KYOWA MEDEX CO LTD (JP) 2004-11-17 EP claimed
US-20040121423-A1 Compositions containing a urea derivative dye for detecting an analyte and methods for using the same CILAG GMBH INTERNATIONAL (CH) 2004-06-24 US claimed
US-6743597-B1 TEST STRIP OF A POSITIVELY CHARGED POROUS MATRIX AND THE DYE 10-(CARBOXYMETHYLAMINOCARBONYL)-3,7-BIS(DIMETHYLAMINO)-PHENOTHIAZINE OR SALT ON THE SURFACE; STORAGE STABILITY FOR AT LEAST SIX MONTHS; DETECTION OF ANALYTES IN BLOOD LIFESCAN, INC. 2004-06-01 US claimed
US-20030211564-A1 Multilayer reagent test strips and methods for using the same to quantify glycated protein in a physiological sample LIFESCAN IP HOLDINGS, LLC 2003-11-13 US claimed
EP-1305624-A2 COMPOSITIONS CONTAINING A UREA DERIVATIVE DYE FOR DETECTING AN ANALYTE Lifescan, Inc. (US) 2003-05-02 EP claimed
WO-2001096596-A2 COMPOSITIONS CONTAINING A UREA DERIVATIVE DYE FOR DETECTING AN ANALYTE LIFESCAN, INC. (US) 2001-12-20 WO claimed
US-6153399-A SIMPLE METHOD FOR QUANTITATIVE DETERMINATION IN SAMPLE BY REACTING IN AQUEOUS MEDIUM ASCORBIC ACID, OXYGEN, ASCORBATE OXIDASE, CHROMOGEN, AND PEROXIDASE; MEASURING ABSORBANCE; COMPARING WITH A CALIBRATION CURVE KYOWA MEDEX CO., LTD. (JP) 2000-11-28 US claimed
EP-0926244-A1 METHODS AND REAGENTS FOR QUANTITATIVELY DETERMINING ASCORBIC ACID KYOWA MEDEX CO., LTD. (JP) 1999-06-30 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11313863-B2 Measurement of glycoprotein HBG1, HBG2, HBB KMT2A 3253/4885MAPK1 1161/4885MEN1 4420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.