Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516237 | 1.00 | CYP2D6 (0.47) | CYP2D6ALDH1A1MAPK1NT5ETSHR | |
| SCHEMBL16317730 | 1.00 | CYP2D6 (0.47) | CYP2D6ALDH1A1MAPK1NT5ETSHR | |
| SCHEMBL22073056 | 0.95 | NT5E (0.53) | CYP2D6ALDH1A1MAPK1NT5ETSHR | |
| SCHEMBL7169887 | 0.93 | NT5E (0.53) | NT5EPTPN1CDC25B | |
| SCHEMBL21537642 | 0.93 | NT5E (0.53) | NT5EPTPN1CDC25B | |
| SCHEMBL24672154 | 0.93 | NT5E (0.53) | NT5EPTPN1CDC25B | |
| SCHEMBL22315183 | 0.93 | NT5E (0.55) | CYP2D6NT5EPTPN1CDC25B | |
| SCHEMBL2485383 | 0.93 | NT5E (0.53) | NT5EPTPN1CDC25B | |
| SCHEMBL19731854 | 0.93 | NT5E (0.53) | NT5EPTPN1CDC25B | |
| SCHEMBL7170086 | 0.93 | NT5E (0.53) | NT5EPTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120258043-A1 | Linkable Lewis X Analogs | BRACCO SUISSE S.A. (CH) | 2012-10-11 | — | — | US | disclosed |
| US-20110229409-A1 | LINKABLE LEWIS X ANALOGS | BRACCO INTERNATIONAL B.V. (NL) | 2011-09-22 | — | — | US | disclosed |
| US-20080300220-A1 | Linkable Lewis X Analogs | BRACCO INTERNATIONAL B.V. (NL) | 2008-12-04 | — | — | US | disclosed |
| US-7422733-B2 | Linkable sialyl Lewis X analogs | BRACCO INTERNATIONAL B.V. (NL) | 2008-09-09 | — | — | US | disclosed |
| US-20040097403-A1 | Linkable sialyl lewis x analogs | BRACCO SUISSE SA (CH) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300220-A1 | Linkable Lewis X Analogs | SSB, SELPLG, SELL | CYP2D6 2973/4885ALDH1A1 1758/4885MAPK1 2022/4885 |
| US-20120258043-A1 | Linkable Lewis X Analogs | SSB, SELPLG, SELL | CYP2D6 2973/4885ALDH1A1 1758/4885MAPK1 2022/4885 |
| US-20040097403-A1 | Linkable sialyl lewis x analogs | SSB, SELPLG, SELL | CYP2D6 3330/4885ALDH1A1 2021/4885MAPK1 1785/4885 |
| US-20110229409-A1 | LINKABLE LEWIS X ANALOGS | SELPLG, SELL, SELE | CYP2D6 1761/4885ALDH1A1 1892/4885MAPK1 1397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.