Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DBH | P09172 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22548736 | 0.94 | KDM4E (0.44) | KDM4EDBHGAARECQLPKM | |
| SCHEMBL21729726 | 0.94 | KDM4E (0.44) | KDM4EDBHGAARECQLPKM | |
| SCHEMBL12377745 | 0.91 | AKR1C3 (0.49) | KDM4EDBHGAARECQLAKR1C3 | |
| SCHEMBL12377744 | 0.91 | AKR1C3 (0.49) | KDM4EAKR1C3AKR1C2AKR1B10AKR1B1 | |
| SCHEMBL21729769 | 0.88 | KDM4E (0.59) | KDM4EDBHGAARECQLNPC1 | |
| SCHEMBL22548887 | 0.86 | GAA (0.47) | KDM4EDBHGAARECQLNPC1 | |
| SCHEMBL20631335 | 0.85 | GAA (0.41) | KDM4EDBHGAARECQLPKM | |
| SCHEMBL20630946 | 0.83 | RECQL (0.42) | KDM4EDBHGAARECQLPKM | |
| SCHEMBL22548962 | 0.79 | KDM4E (0.39) | KDM4EDBHGAARECQLNPC1 | |
| SCHEMBL12377747 | 0.78 | ACE2 (0.51) | KDM4EDBHGAARECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022118186-A1 | SENOTHERAPEUTIC COMPOUND | BIONEXA S.R.L. (IT) | 2022-06-09 | — | — | WO | disclosed |