Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 16/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 16/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DBH | P09172 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377744 | 0.93 | AKR1C3 (0.49) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL24497178 | 0.91 | KDM4E (0.46) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL12377747 | 0.89 | ACE2 (0.51) | CDC25ACDC25BHSD17B10ALDH1A1POLB | |
| SCHEMBL21729726 | 0.89 | KDM4E (0.44) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL22548736 | 0.85 | KDM4E (0.44) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL7823608 | 0.85 | CDC25A (0.59) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL16261358 | 0.83 | AKR1C3 (0.57) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL21729769 | 0.79 | KDM4E (0.59) | CDC25ACDC25BHSD17B10ALDH1A1TDP1 | |
| SCHEMBL4623376 | 0.79 | AKR1C3 (0.57) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL20630946 | 0.79 | RECQL (0.42) | CDC25ACDC25BHSD17B10ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969303-B2 | Tocotrienol esters | FIRST TECH INTERNATIONAL LIMITED (CN) | 2015-03-03 | — | — | US | disclosed |
| US-20110196030-A1 | TOCOTRIENOL ESTERS | FIRST TECH INTERNATIONAL LIMITED (CN) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110196030-A1 | TOCOTRIENOL ESTERS | TTPA, MBOAT1, TBXAS1 | AKR1C3 1396/4885AKR1C2 1677/4885AKR1B10 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.