Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 11/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24497569 | 0.83 | ALOX15 (0.36) | TYK2KMT2AJAK1SCN9ASCN4A | |
| SCHEMBL16963976 | 0.81 | TLR8 (0.46) | TYK2KMT2AJAK1JAK2JAK3 | |
| SCHEMBL17207255 | 0.78 | TYK2 (0.40) | TYK2JAK1SCN9AJAK2 | |
| SCHEMBL24497567 | 0.76 | JMJD6 (0.42) | TYK2KMT2AJAK1SCN9ATLR8 | |
| SCHEMBL18378772 | 0.74 | KMT2A (0.47) | TYK2KMT2AJAK1SCN4AJAK2 | |
| SCHEMBL29767299 | 0.73 | KMT2A (0.55) | TYK2KMT2AJAK1JAK2JAK3 | |
| SCHEMBL16574032 | 0.73 | KMT2A (0.55) | TYK2KMT2AJAK1JAK2JAK3 | |
| SCHEMBL9688509 | 0.73 | SCN4A (0.42) | KMT2ASCN9ASCN4ACYP3A4 | |
| SCHEMBL17207235 | 0.72 | TYK2 (0.38) | TYK2KMT2AJAK1SCN9AADRA1D | |
| SCHEMBL18104707 | 0.70 | TLR8 (0.40) | TYK2KMT2AJAK1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257587-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |