Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 13/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | KRAS | P01116 | 3/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18521681 | 0.93 | RNASEL (0.62) | RNASELNT5EKRASTGM2 | |
| SCHEMBL21943191 | 0.92 | RNASEL (0.63) | RNASELADORA1 | |
| SCHEMBL24499056 | 0.90 | RNASEL (0.55) | RNASELNT5EKRASTGM2ADORA1 | |
| SCHEMBL24499234 | 0.88 | NT5E (0.54) | RNASELNT5EKRASTGM2ADORA1 | |
| SCHEMBL22381711 | 0.88 | NT5E (0.55) | RNASELNT5EKRASTGM2ADORA1 | |
| SCHEMBL24499555 | 0.87 | RNASEL (0.56) | RNASELNT5EKRASTGM2ADORA1 | |
| SCHEMBL18521781 | 0.87 | RNASEL (0.57) | RNASELNT5EADORA1 | |
| SCHEMBL24499573 | 0.86 | RNASEL (0.57) | RNASELNT5EADORA1 | |
| SCHEMBL22381537 | 0.86 | NT5E (0.54) | NT5EKRASTGM2 | |
| SCHEMBL22381798 | 0.86 | RNASEL (0.56) | RNASELNT5ETGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220175811-A1 | STABLE FORMULATIONS OF CYCLIC DINUCLEOTIDE STING AGONIST COMPOUNDS AND METHODS OF USE THEREOF | MERCK SHARP & DOHME CORP. (US) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220175811-A1 | STABLE FORMULATIONS OF CYCLIC DINUCLEOTIDE STING AGONIST COMPOUNDS AND METHODS OF USE THEREOF | STING1, CGAS, IRF3 | RNASEL 1846/4885NT5E 56/4885KRAS 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.