Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.38 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | TK2 | O00142 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24244831 | 1.00 | TK1 (0.38) | TK1RNASE1HPGDNT5ENT5M | |
| SCHEMBL24244849 | 1.00 | TK1 (0.38) | TK1RNASE1HPGDNT5ENT5M | |
| SCHEMBL22609161 | 0.88 | TK1 (0.36) | TK1RNASE1HPGDNT5MBCHE | |
| SCHEMBL22609159 | 0.88 | TK1 (0.36) | TK1RNASE1HPGDNT5MBCHE | |
| SCHEMBL23054795 | 0.88 | TK1 (0.36) | TK1RNASE1HPGDNT5MBCHE | |
| SCHEMBL13396754 | 0.88 | NT5E (0.43) | NT5E | |
| SCHEMBL7214746 | 0.88 | NT5E (0.43) | NT5E | |
| SCHEMBL7209722 | 0.88 | NT5E (0.43) | NT5E | |
| SCHEMBL22609149 | 0.88 | TK1 (0.43) | TK1HPGDNT5ETK2 | |
| SCHEMBL21085681 | 0.88 | TK1 (0.43) | TK1HPGDNT5ETK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177509-A1 | PRODUCTION OF BRIDGED ARTIFICIAL NUCLEOSIDES | NIPPON SHOKUBAI CO., LTD. (JP) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177509-A1 | PRODUCTION OF BRIDGED ARTIFICIAL NUCLEOSIDES | TYMP, PNP, TYMS | TK1 78/4885RNASE1 200/4885HPGD 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.