Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290102 | 0.88 | TPMT (0.48) | MEN1KMT2ACRHBPCRHR2TPMT | |
| SCHEMBL21567703 | 0.81 | MCL1 (0.49) | DHODHMEN1KMT2ASMN1; SMN2RXRA | |
| SCHEMBL28888036 | 0.79 | AKR1C2 (0.45) | NOTUMSMN1; SMN2KDM4ETTRRARA | |
| SCHEMBL19585743 | 0.78 | KDM4E (0.48) | DHODHMEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL17831135 | 0.78 | KDM4E (0.48) | MEN1KMT2ACRHBPCRHR2TPMT | |
| SCHEMBL17177745 | 0.77 | AKR1C2 (0.44) | NOTUMSMN1; SMN2KDM4ETTRRARA | |
| SCHEMBL7737301 | 0.77 | NOTUM (0.37) | DHODHMEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL15462913 | 0.76 | CYP3A4 (0.48) | MEN1KMT2ACRHBPCRHR2TPMT | |
| SCHEMBL24492690 | 0.75 | RARB (0.48) | DHODHMEN1KMT2AKDM4ERARA | |
| SCHEMBL10018717 | 0.74 | HDAC1 (0.39) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022117551-A1 | LIQUID CRYSTALLINE MEDIUM AND ELECTRO-OPTICAL DEVICE | MERCK PATENT GMBH (DE) | 2022-06-09 | — | — | WO | disclosed |