Emetine

Emetine

SCHEMBL56277

CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]1NCCc2cc(OC)c(OC)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 1.00
MEN1 O00255 6/20 1.00
KMT2A Q03164 6/20 1.00
SMN1; SMN2 Q16637 5/20 1.00
SLC2A1 P11166 5/20 1.00
LMNA P02545 4/20 1.00
CYP3A4 P08684 3/20 1.00
MAPK1 P28482 3/20 1.00
NPC1 O15118 3/20 1.00
RAB9A P51151 3/20 1.00
EPAS1 Q99814 3/20 1.00
MAPT P10636 2/20 1.00
STAT6 P42226 2/20 1.00
TP53 P04637 1/20 1.00
NFKB1 P19838 1/20 1.00
THPO P40225 1/20 1.00
HTT P42858 1/20 1.00
RBBP9 O75884 1/20 1.00
ABCB1 P08183 1/20 1.00
HTR1A P08908 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Emetine SCHEMBL14135123 1.00 HIF1A (1.00) HIF1AMEN1KMT2ASMN1; SMN2SLC2A1
Emetine SCHEMBL29392786 1.00 HIF1A (1.00) HIF1AMEN1KMT2ASMN1; SMN2SLC2A1
Emetine SCHEMBL14261157 1.00 HIF1A (1.00) HIF1AMEN1KMT2ASMN1; SMN2SLC2A1
Emetine SCHEMBL29390500 1.00 HIF1A (1.00) HIF1AMEN1KMT2ASMN1; SMN2SLC2A1
Emetine SCHEMBL13226748 1.00 HIF1A (1.00) HIF1AMEN1KMT2ASMN1; SMN2SLC2A1
Emetine SCHEMBL14269958 1.00 HIF1A (1.00) HIF1AMEN1KMT2ASMN1; SMN2SLC2A1
Emetine SCHEMBL24499457 1.00 HIF1A (1.00) HIF1AMEN1KMT2ASMN1; SMN2SLC2A1
Emetine SCHEMBL14029342 1.00 HIF1A (1.00) HIF1AMEN1KMT2ASMN1; SMN2SLC2A1
Emetine SCHEMBL13912579 1.00 HIF1A (1.00) HIF1AMEN1KMT2ASMN1; SMN2SLC2A1
Emetine SCHEMBL2382448 0.99 MEN1 (1.00) HIF1AMEN1KMT2ASMN1; SMN2SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 23021 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137650-A1 MODULATORS OF RAR RELATED ORPHAN RECEPTORS (RORs) 11949098 CANADA INC (CA) 2026-05-21 US claimed
WO-2026087680-A1 TREATMENT FOR CARDIOVASCULAR DISEASE SAPREME TECHNOLOGIES B.V. (NL) 2026-04-30 WO claimed
WO-2026087695-A1 TREATMENT FOR METABOLIC DISORDER SAPREME TECHNOLOGIES B.V. (NL) 2026-04-30 WO claimed
EP-4709383-A1 INVERSE AGONISTS OF RAR RELATED ORPHAN RECEPTORS (RORS) 11949098 Canada Inc. (CA) 2026-03-18 EP claimed
US-12577324-B2 Antibodies having specificity to HER4 and uses thereof INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2026-03-17 US claimed
EP-4704811-A1 MODIFIED LIPOSOME FOR DRUG DELIVERY, USE OF LIPOSOME FOR DRUG DELIVERY, ESPECIALLY WITH ANTI-CANCER ACTIVITY, AND WAYS TO LOAD LIPOSOME WITH DRUGS, ESPECIALLY WITH ANTI-CANCER ACTIVITY BS Biotechna Spolka Akcyjna (PL) 2026-03-11 EP claimed
EP-4704812-A1 A PHARMACEUTICAL COMPOSITION COMPRISING EMETINE AND MITOXANTRONE FOR THE PREVENTION OR TREATMENT OF MAMMARY GLAND CANCER AND A LIPOSOME CONTAINING THIS COMPOSITION BS Biotechna Spolka Akcyjna (PL) 2026-03-11 EP claimed
US-12550885-B2 Red blood cell storage solutions, solution additives, and methods for improving the storage of red blood cells UNIVERSITY OF CINCINNATI (US) 2026-02-17 US claimed
US-20250381202-A1 PRODRUG KIT FOR MULTI-PRONGED CHEMOTHERAPY ZOUNEK ALEX (DE) 2025-12-18 US claimed
EP-4658278-A1 SELECTIVE FIASMA TREATMENT Valo Health, Inc. (US) 2025-12-10 EP claimed
EP-0037175-B1 PHARMACEUTICAL COMPOSITIONS EFAMOL LIMITED (GB) 1988-02-10 EP claimed
EP-0239102-A2 Process for the formation of human-human hybridoma Tsuji, Kimiyoshi (JP) 1987-09-30 EP claimed
US-4675295-A Process for producing subculturable lymphokine-producing human T cell hybridomas DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-06-23 US claimed
EP-0174810-A2 Multidrug resistance in mammalian cell lines and isolation of determinant glycoprotein DNA HSC Research Development Corporation (CA) 1986-03-19 EP claimed
US-4529583-A Composition and method of immobilizing emetics and method of treating human beings with emetics CLEAR LAKE DEVELOPMENT GROUP (US) 1985-07-16 US claimed
US-4459278-A Composition and method of immobilizing emetics and method of treating human beings with emetics CLEAR LAKE DEVELOPMENT GROUP (US) 1984-07-10 US claimed
EP-0035856-B1 PHARMACEUTICAL AND DIETARY COMPOSITIONS EFAMOL LIMITED (GB) 1984-07-04 EP claimed
EP-0037175-A1 Pharmaceutical compositions EFAMOL LIMITED (GB) 1981-10-07 EP claimed
EP-0035856-A2 Pharmaceutical and dietary compositions EFAMOL LIMITED (GB) 1981-09-16 EP claimed
US-4175119-A Composition and method to prevent accidental and intentional overdosage with psychoactive drugs PORTER GARRY L 1979-11-20 US claimed