Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290206 | 0.86 | NPC1 (0.61) | NPC1MAPTALOX5MTORF10 | |
| SCHEMBL6290205 | 0.86 | NPC1 (0.61) | NPC1MAPTALOX5MTORF10 | |
| SCHEMBL30259901 | 0.85 | NPC1 (0.59) | NPC1MAPTALOX5MTORF10 | |
| SCHEMBL17570500 | 0.85 | AOC3 (0.65) | NPC1MAPTALOX5MTORF10 | |
| SCHEMBL4075832 | 0.85 | GAA (0.64) | NPC1MAPTALOX5MTORLMNA | |
| SCHEMBL8480688 | 0.83 | PKM (0.53) | MAPTLMNAAOC3 | |
| SCHEMBL29625240 | 0.83 | NPC1 (0.61) | NPC1F7HPGDL3MBTL1 | |
| SCHEMBL24499496 | 0.83 | NPC1 (0.61) | NPC1F7HPGDL3MBTL1 | |
| SCHEMBL1750050 | 0.82 | CYP1A2 (0.58) | NPC1MAPTALOX5MTORF10 | |
| SCHEMBL10320867 | 0.82 | F10 (0.57) | NPC1MAPTALOX5MTORF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116963733-A | Imidazole compounds as ENPP1 inhibitors | 斯汀格瑞治疗股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| EP-4255425-A1 | IMIDAZOLE COMPOUNDS AS INHIBITORS OF ENPP1 | Stingray Therapeutics, Inc. (US) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022119928-A1 | IMIDAZOLE COMPOUNDS AS INHIBITORS OF ENPP1 | Stingray Therapeutics, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |
| WO-2022119928-A1 | IMIDAZOLE COMPOUNDS AS INHIBITORS OF ENPP1 | Stingray Therapeutics, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |