Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 17/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2450529 | 0.97 | TRPA1 (0.53) | TRPA1MAPTSMN1; SMN2 | |
| SCHEMBL2439039 | 0.95 | TRPA1 (0.59) | TRPA1MAPTSMN1; SMN2 | |
| SCHEMBL2445806 | 0.95 | MAPT (0.53) | TRPA1MAPTSMN1; SMN2 | |
| SCHEMBL2451770 | 0.92 | TRPA1 (0.57) | TRPA1MAPTSMN1; SMN2 | |
| SCHEMBL2452340 | 0.92 | MAPT (0.52) | TRPA1MAPTSMN1; SMN2 | |
| SCHEMBL2445568 | 0.89 | TRPA1 (0.58) | TRPA1MAPTSMN1; SMN2 | |
| SCHEMBL2449784 | 0.88 | TRPA1 (0.58) | TRPA1MAPTSMN1; SMN2 | |
| SCHEMBL2439954 | 0.88 | TRPA1 (0.67) | TRPA1MAPTSMN1; SMN2 | |
| SCHEMBL2445785 | 0.88 | TRPA1 (0.59) | TRPA1MAPTSMN1; SMN2 | |
| SCHEMBL2450658 | 0.88 | TRPA1 (0.69) | TRPA1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011114184-A1 | AMIDES OF HETEROCYCLIC COMPOUNDS AS TRPA1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-09-22 | — | — | WO | claimed |
| WO-2011114184-A1 | AMIDES OF HETEROCYCLIC COMPOUNDS AS TRPA1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-09-22 | — | — | WO | disclosed |