Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 9/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30411459 | 0.89 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL19171831 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL20466960 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL872772 | 0.85 | BRD4 (0.49) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL872773 | 0.85 | BRD4 (0.49) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL15281425 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL23728786 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL19136021 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL31498738 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL24182336 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAHPGDPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177490-A1 | COMPOUNDS HAVING BOTH EFFECTS OF BET BROMODOMAIN PROTEIN INHIBITION AND PD-L1 GENE REGULATION | MEDSHINE DISCOVERY INC. (CN) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177490-A1 | COMPOUNDS HAVING BOTH EFFECTS OF BET BROMODOMAIN PROTEIN INHIBITION AND PD-L1 GENE REGULATION | BET1, BRD4, BRD3 | ALDH1A1 2723/4885MAPT 2624/4885LMNA 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.