Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24500388 | 0.87 | MEN1 (0.62) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL24500391 | 0.84 | MEN1 (0.40) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL30733540 | 0.78 | MEN1 (0.60) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL438540 | 0.78 | MEN1 (0.75) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL18818825 | 0.77 | MEN1 (0.63) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL17970032 | 0.77 | MEN1 (0.58) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL18818826 | 0.76 | MEN1 (0.68) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL17367816 | 0.75 | MEN1 (0.79) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL13113782 | 0.75 | MEN1 (0.72) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL17970040 | 0.75 | MEN1 (0.79) | MEN1KMT2AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022117473-A1 | HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-06-09 | — | — | WO | disclosed |