Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29694771 | 1.00 | POLB (0.33) | POLBGAA | |
| SCHEMBL24500507 | 0.92 | POLB (0.33) | POLBGAA | |
| SCHEMBL24500874 | 0.90 | POLB (0.35) | POLBGAA | |
| SCHEMBL27293926 | 0.90 | POLB (0.35) | POLBGAA | |
| SCHEMBL24500949 | 0.87 | POLB (0.33) | POLBGAA | |
| SCHEMBL29694653 | 0.85 | POLB (0.32) | POLBGAA | |
| SCHEMBL24770003 | 0.80 | POLB (0.31) | POLBGAA | |
| SCHEMBL24770145 | 0.79 | POLB (0.33) | POLBGAA | |
| SCHEMBL24501492 | 0.77 | POLB (0.33) | POLBGAA | |
| SCHEMBL24501495 | 0.77 | POLB (0.33) | POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022118210-A1 | SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2022-06-09 | — | — | WO | disclosed |