Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 8/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31678313 | 1.00 | EIF4E (0.42) | EIF4EPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL24501645 | 0.93 | EIF4E (0.42) | EIF4EPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31678340 | 0.93 | EIF4E (0.42) | EIF4EPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31678341 | 0.87 | APAF1 (0.41) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL24500632 | 0.87 | APAF1 (0.41) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL24501681 | 0.87 | EIF4E (0.40) | EIF4EPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31678529 | 0.84 | MEN1 (0.41) | EIF4EMEN1KMT2APOLBAKR1C3 | |
| SCHEMBL24501639 | 0.84 | MEN1 (0.41) | EIF4EMEN1KMT2APOLBAKR1C3 | |
| SCHEMBL24501091 | 0.81 | POLB (0.41) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL29830842 | 0.81 | POLB (0.41) | MEN1KMT2APOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022117445-A1 | HERBICIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-09 | — | — | WO | disclosed |