Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.68 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29648408 | 1.00 | CRBN (0.68) | CRBNDDB1PBRM1MIFMAP1LC3B | |
| SCHEMBL31443804 | 0.88 | CRBN (0.68) | CRBNDDB1 | |
| SCHEMBL22940154 | 0.85 | CRBN (0.68) | CRBNDDB1 | |
| SCHEMBL30121132 | 0.82 | CRBN (0.63) | CRBNDDB1 | |
| SCHEMBL824532 | 0.82 | CRBN (0.63) | CRBNDDB1 | |
| SCHEMBL31443840 | 0.81 | CRBN (0.80) | CRBN | |
| SCHEMBL31443974 | 0.81 | CRBN (1.00) | CRBN | |
| SCHEMBL24319166 | 0.79 | CRBN (0.60) | CRBNDDB1 | |
| SCHEMBL27098105 | 0.78 | CRBN (0.59) | CRBNDDB1MIF | |
| SCHEMBL31347063 | 0.78 | CRBN (0.58) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120355-A1 | TEAD DEGRADERS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |