SCHEMBL31443804

SCHEMBL31443804

CN1C(=O)CCC(N2Cc3ccc(Br)cc3C2=O)C1=O

nearest known ligand 0.68

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 17/20 0.68
▸ SRD5A1 P18405 2/20 0.40
▸ DDB1 Q16531 2/20 0.38
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31347063 0.90 CRBN (0.58) CRBNSRD5A1DDB1
SCHEMBL26107723 0.90 CRBN (0.58) CRBNSRD5A1DDB1
SCHEMBL29648408 0.88 CRBN (0.68) CRBNDDB1
SCHEMBL24501885 0.88 CRBN (0.68) CRBNDDB1
SCHEMBL22940154 0.85 CRBN (0.68) CRBNDDB1
SCHEMBL30121132 0.82 CRBN (0.63) CRBNSRD5A1DDB1KMT2A
SCHEMBL824532 0.82 CRBN (0.63) CRBNSRD5A1DDB1KMT2A
SCHEMBL31443840 0.81 CRBN (0.80) CRBN
SCHEMBL31443974 0.81 CRBN (1.00) CRBN
SCHEMBL18766133 0.80 MAPK1 (0.49) CRBNMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
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