Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15893906 | 1.00 | EPHX2 (0.41) | EPHX2JAK2JAK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5221714 | 0.98 | EPHX2 (0.40) | EPHX2JAK2JAK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5221768 | 0.98 | EPHX2 (0.40) | EPHX2JAK2JAK1MEN1KMT2A | |
| SCHEMBL14136755 | 0.89 | MEN1 (0.41) | EPHX2JAK2JAK1MEN1KMT2A | |
| SCHEMBL1517111 | 0.88 | EPHX2 (0.46) | EPHX2JAK2JAK1FAAHHRH3 | |
| Hydrochloric Acid SCHEMBL5215157 | 0.86 | EPHX2 (0.45) | EPHX2JAK2JAK1FAAHHRH3 | |
| SCHEMBL19413968 | 0.82 | EPHX2 (0.41) | EPHX2JAK2JAK1MEN1KMT2A | |
| SCHEMBL20243572 | 0.82 | EPHX2 (0.41) | EPHX2JAK2JAK1MEN1KMT2A | |
| SCHEMBL18251644 | 0.82 | EPHX2 (0.41) | EPHX2JAK2JAK1MEN1KMT2A | |
| SCHEMBL10280127 | 0.78 | EPHX2 (0.41) | EPHX2JAK2JAK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120355-A1 | TEAD DEGRADERS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |