Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 5/20 | 0.62 |
| ▸ | ADH1A | P07327 | 5/20 | 0.62 |
| ▸ | ADH1C | P00326 | 4/20 | 0.62 |
| ▸ | ADH7 | P40394 | 3/20 | 0.62 |
| ▸ | ADH4 | P08319 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24500875 | 0.80 | ADH1B (0.73) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL115509 | 0.78 | — | — | |
| SCHEMBL20065985 | 0.75 | — | — | |
| SCHEMBL20065981 | 0.75 | — | — | |
| SCHEMBL20065998 | 0.75 | — | — | |
| SCHEMBL22883812 | 0.74 | ADH1B (0.62) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL22883564 | 0.74 | ADH1B (0.62) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL20678788 | 0.74 | ADH1B (0.62) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL1766618 | 0.74 | ADH1B (0.62) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL13572444 | 0.74 | ADH1B (0.62) | ADH1BADH1AADH1CADH7ADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120355-A1 | TEAD DEGRADERS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |