Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | ACACA | Q13085 | 3/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PDE7B | Q9NP56 | 9/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2525634 | 0.93 | ACACB (0.37) | SLC6A4SLC6A3ACACBACACA | |
| SCHEMBL728664 | 0.85 | ACACB (0.36) | ACACBACACAPDE7APDE7B | |
| SCHEMBL9410107 | 0.85 | NPC1 (0.31) | — | |
| SCHEMBL4498709 | 0.84 | — | — | |
| SCHEMBL12496990 | 0.84 | PDE7A (0.43) | PDE7APDE7B | |
| SCHEMBL2446968 | 0.81 | — | — | |
| SCHEMBL3902215 | 0.78 | CES1 (0.33) | PDE7A | |
| SCHEMBL12496896 | 0.77 | PDE7A (0.40) | PDE7A | |
| SCHEMBL6290225 | 0.76 | ACACB (0.43) | ACACBACACA | |
| SCHEMBL3397819 | 0.76 | SLC6A4 (0.33) | SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410289-B2 | Spirocyclic 3'-alkoxytetramic acids and-tetronic acids | BAYER CROPSCIENCE AG (DE) | 2013-04-02 | — | — | US | disclosed |
| EP-1761490-B1 | 3'-ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2011-09-07 | — | — | EP | disclosed |
| EP-2246328-A1 | 3'-Alkoxy spirocyclic tetronic acid derivatives | Bayer CropScience AG (DE) | 2010-11-03 | — | — | EP | disclosed |
| US-20090029858-A1 | Spirocyclic 3'-Alkoxytetramic Acids and -Tetronic Acids | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029858-A1 | Spirocyclic 3'-Alkoxytetramic Acids and -Tetronic Acids | DDT, MTX1, MTX2 | SLC6A4 3627/4885SLC6A3 2585/4885ACACB 505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.