MTX2

Metaxin-2 · O75431 · MTX2 on Sugi Atlas →

0 patent compounds predicted against MTX2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to MTX2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Methotrexate in Patients with Early Rheumatoid Arthritis PHASE4ACTIVE_NOT_RECRUITING
Immune Modulation During Palynziq® Treatment in Adults (IMPALA) PHASE4RECRUITING
Subcuteous Methotrexate in Rheumatoid Arthritis PHASE4COMPLETED
Methotrexate Polyglutamate Levels as a Marker for the Clinical Outcome in the Treatment of Rheumatoid Arthritis PHASE4COMPLETED
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations PHASE3RECRUITING
Extension Study of Tocilizumab Long Term Treatment of Moderate to Severe Rheumatoid Arthritis Patients PHASE3COMPLETED
Study of Safety and Efficacy of HLX01+MTX in Patients With Rheumatoid Arthritis PHASE3COMPLETED
Phase III Study of Vinflunine Plus Methotrexate Versus Methotrexate Alone in Patients With Head and Neck Cancer PHASE3COMPLETED
Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia PHASE3ACTIVE_NOT_RECRUITING
A Study Comparing SB2 to Remicade® in Subjects With Moderate to Severe Rheumatoid Arthritis Despite Methotrexate Therapy PHASE3COMPLETED
Combination Chemotherapy in Treating Children With Anaplastic Large Cell Lymphoma (ALCL 99) PHASE3COMPLETED
Study of Glucarpidase (CPG2) for the Management of Patients With Delayed Methotrexate Clearance PHASE2COMPLETED
A Phase I/II Study to Investigate the Use of VORAXAZE™ As Intended Intervention in Patients with CNSL PHASE1/PHASE2COMPLETED
An Open-Label Extension Study Assessing the Long-Term Efficacy and Safety of ALX-0061 in Subjects With Rheumatoid Arthritis PHASE2COMPLETED
An Adaptive Design Study of MTX228 PHASE2RECRUITING
EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc) PHASE2RECRUITING
WJMSCs Anti-inflammatory Therapy in Coronary Artery Disease PHASE2UNKNOWN
Modified BFM-95 Regimen as First-Line Chemotherapy in Adults With T- Lymphoblastic Lymphoma PHASE2UNKNOWN
Radiation Therapy and Chemotherapy in Treating Children With CNS Relapse From Acute Lymphoblastic Leukemia PHASE2COMPLETED
Methotrexate and Metformin in Rheumatoid Arthritis Patients PHASE2ACTIVE_NOT_RECRUITING
A Trial of Carboxypeptidase-G2 (CPDG2) and Thymidine for the Management of Patients With Methotrexate Toxicity and Renal Dysfunction PHASE1COMPLETED
A First-in-Human Safety Trial of MTX-474 PHASE1COMPLETED
Combination Therapy of F8IL10 and Methotrexate in Rheumatoid Arthritis Patients PHASE1COMPLETED
Glucarpidase After High-Dose Methotrexate in Patients With Osteosarcoma EARLY_PHASE1ACTIVE_NOT_RECRUITING
Prediction of Excretion and Toxicity of High Dose Methotrexate in Children and Adolescents With ALL nanCOMPLETED
Understanding Methotrexate Induced Gastrointestinal Intolerance in Juvenile Idiopathic Arthritis and Childhood Leukemia nanCOMPLETED
Carboxypeptidase-G2 in Treating Nervous System Toxic Effects in Patients Given an Overdose of Intrathecal Methotrexate nanCOMPLETED
Renal and Hepatic Clearance Following High-Dose Methotrexate in Childhood ALL nanCOMPLETED
Study for Treatment of Cancer in Children With Ataxia-telangiectasia nanCOMPLETED
Card14gene (rs34367357 ) Polymorphism in Egyptian Psoriatic and Psoriatic Arthritis Patient nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a MTX2 binder may also engage these)

ProteinNameSimilarity
Q2L969 1.000 Q2L969 →
O88441 1.000 O88441 →
Q5HYI7 0.975 Q5HYI7 →
Q9ER88 0.958 Q9ER88 →
Q3KPT9 0.955 Q3KPT9 →
O93479 0.955 O93479 →
P82922 0.954 P82922 →
O88741 0.953 O88741 →
DAP3 Small ribosomal subunit protein mS29 0.953 landscape →
G1SPE9 0.952 G1SPE9 →
Q80YQ8 0.951 Q80YQ8 →
GNPAT Dihydroxyacetone phosphate acyltransferase 0.951 landscape →
Q5IH13 0.950 Q5IH13 →
A6H611 0.950 A6H611 →
Q58E26 0.950 Q58E26 →
Q8TB36 0.950 Q8TB36 →
Q5RGJ5 0.949 Q5RGJ5 →
Q5R8R4 0.949 Q5R8R4 →
Q8R455 0.949 Q8R455 →
Q9H871 0.949 Q9H871 →
GSTO1 Glutathione S-transferase omega-1 0.948 landscape →
Q6DFF4 0.948 Q6DFF4 →
Q9DCM2 0.948 Q9DCM2 →
Q32LU1 0.948 Q32LU1 →
Q01992 0.947 Q01992 →
Q8R4D5 0.947 Q8R4D5 →
Q9D1E8 0.947 Q9D1E8 →
Q8K114 0.947 Q8K114 →
P98192 0.947 P98192 →
A2RU49 0.947 A2RU49 →