Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 2/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 3/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.44 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24195929 | 0.89 | PRKDC (0.47) | WDR91PRKDCNOTUMHSD17B10GLA | |
| SCHEMBL24195922 | 0.89 | PRKDC (0.47) | WDR91PRKDCNOTUMHSD17B10GLA | |
| SCHEMBL2449550 | 0.84 | NOTUM (0.61) | WDR91PRKDCNOTUMHSD17B10GLA | |
| SCHEMBL2452218 | 0.82 | BPTF (0.52) | PRKDCNOTUMDPP4DPP9DPP7 | |
| SCHEMBL2451481 | 0.81 | WDR91 (0.66) | WDR91PRKDCNOTUMHSD17B10GLA | |
| SCHEMBL2449229 | 0.81 | NOTUM (0.64) | WDR91PRKDCNOTUMHSD17B10GLA | |
| SCHEMBL79756 | 0.80 | WDR91 (0.52) | WDR91PRKDCNOTUMHSD17B10GLA | |
| SCHEMBL22491869 | 0.80 | NOTUM (0.59) | NOTUMALDH1A1 | |
| SCHEMBL22655697 | 0.80 | NOTUM (0.59) | NOTUMALDH1A1 | |
| SCHEMBL29621605 | 0.80 | NOTUM (0.53) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362775-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2011-09-07 | — | — | EP | disclosed |