Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 3/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2449229 | 0.85 | NOTUM (0.64) | ALDH1A1MEN1KMT2ANOTUMPRKDC | |
| SCHEMBL2445431 | 0.84 | NOTUM (0.65) | ALDH1A1MEN1KMT2ANOTUMPRKDC | |
| SCHEMBL29735291 | 0.83 | HSD11B1 (0.49) | BPTFALDH1A1MEN1KMT2AHSD11B1 | |
| SCHEMBL2449550 | 0.83 | NOTUM (0.61) | ALDH1A1FPR2SCN9AMEN1KMT2A | |
| SCHEMBL2446475 | 0.83 | KMT2A (0.62) | ALDH1A1MEN1KMT2ANOTUMPRKDC | |
| SCHEMBL2450319 | 0.82 | WDR91 (0.48) | ALDH1A1FPR2SCN9ANOTUMPRKDC | |
| SCHEMBL2449553 | 0.82 | MTNR1A (0.51) | MEN1KMT2ANOTUM | |
| SCHEMBL24195922 | 0.80 | PRKDC (0.47) | ALDH1A1FPR2SCN9AMEN1KMT2A | |
| SCHEMBL24195929 | 0.80 | PRKDC (0.47) | ALDH1A1FPR2SCN9AMEN1KMT2A | |
| SCHEMBL2557961 | 0.79 | NOTUM (0.72) | BPTFNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362775-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2011-09-07 | — | — | EP | disclosed |