Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ACP1 | P24666 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19096372 | 0.81 | CFTR (0.52) | ALDH1A1MAPTHPGDCYP3A4CYP2C9 | |
| SCHEMBL19096626 | 0.70 | CFTR (0.53) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL19096416 | 0.65 | FAAH (0.50) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL19096234 | 0.65 | S1PR1 (0.44) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL17302129 | 0.64 | S1PR1 (0.70) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL20582539 | 0.64 | S1PR1 (0.67) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL19096576 | 0.64 | S1PR1 (0.55) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL17309309 | 0.63 | CA9 (0.76) | ALDH1A1MAPTHPGDCYP3A4CYP2C9 | |
| SCHEMBL19481512 | 0.63 | CA9 (0.76) | ALDH1A1MAPTHPGDCYP3A4CYP2C9 | |
| SCHEMBL19096560 | 0.63 | S1PR1 (0.49) | ALDH1A1MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4011879-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2022-06-15 | — | — | EP | disclosed |