Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 14/20 | 0.64 |
| ▸ | HINT1 | P49773 | 1/20 | 0.59 |
| ▸ | STAT6 | P42226 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20435031 | 0.92 | SLC29A1 (0.72) | SLC29A1HINT1STAT6ADORA1TP53 | |
| SCHEMBL20435030 | 0.91 | SLC29A1 (0.60) | SLC29A1STAT6ADORA1TP53CYP3A4 | |
| SCHEMBL24505727 | 0.85 | ADORA1 (0.65) | SLC29A1HINT1ADORA1TP53 | |
| SCHEMBL24505763 | 0.85 | SLC29A1 (0.70) | SLC29A1STAT6TP53CYP3A4HIF1A | |
| SCHEMBL20434985 | 0.85 | SLC29A1 (0.70) | SLC29A1STAT6TP53CYP3A4HIF1A | |
| SCHEMBL1000840 | 0.80 | HINT1 (0.78) | HINT1ADORA1 | |
| SCHEMBL7226454 | 0.80 | HINT1 (0.78) | HINT1ADORA1 | |
| SCHEMBL24505864 | 0.80 | SLC29A1 (0.57) | SLC29A1TP53CYP3A4HIF1AABCC4 | |
| SCHEMBL29697175 | 0.78 | ADORA1 (0.66) | SLC29A1ADORA1 | |
| SCHEMBL20435005 | 0.78 | ADORA1 (0.66) | SLC29A1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573996-B1 | COMPOUND WITH ANALGESIC EFFECT FOR USE IN PREVENTION AND TREATMENT OF PAIN | ACADEMIA SINICA (TW) | 2022-06-15 | — | — | EP | disclosed |