SCHEMBL24507873

SCHEMBL24507873

CCCN(OCCN)C(=O)C1=Cc2ccc(-c3cnccc3C)cc2N=C(N)C1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TLR8 Q9NR97 20/20 0.56
▸ TLR7 Q9NYK1 6/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27078295 0.87 TLR8 (0.51) TLR8TLR7
SCHEMBL30876971 0.87 TLR8 (0.49) TLR8TLR7
SCHEMBL24507423 0.85 TLR8 (0.73) TLR8TLR7
SCHEMBL27079479 0.82 TLR8 (0.56) TLR8TLR7
SCHEMBL24699323 0.81 TLR8 (0.55) TLR8TLR7
SCHEMBL30823600 0.80 TLR8 (0.48) TLR8TLR7
SCHEMBL27078474 0.80 TLR8 (0.48) TLR8TLR7
SCHEMBL24699264 0.80 TLR8 (0.55) TLR8TLR7
SCHEMBL30876972 0.80 TLR8 (0.42) TLR8TLR7
SCHEMBL27078437 0.79 TLR8 (0.50) TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313161-A1 2-AMINO-4-CARBOXAMIDE-BENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF Bolt Biotherapeutics, Inc. (US) 2024-02-07 — — EP disclosed
WO-2022125904-A1 ANTI-HER2 IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2022-06-16 — — WO disclosed
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