SCHEMBL27078295

SCHEMBL27078295

CCCN(OCCN)C(=O)C1=Cc2ccncc2N=C(N)C1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TLR8 Q9NR97 20/20 0.51
▸ TLR7 Q9NYK1 6/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27079094 0.89 TLR8 (0.46) TLR8TLR7
SCHEMBL27078280 0.89 TLR8 (0.48) TLR8TLR7
SCHEMBL24507873 0.87 TLR8 (0.56) TLR8TLR7
SCHEMBL30823600 0.87 TLR8 (0.48) TLR8TLR7
SCHEMBL27078268 0.87 TLR8 (0.44) TLR8TLR7
SCHEMBL27078474 0.87 TLR8 (0.48) TLR8TLR7
SCHEMBL30945298 0.85 TLR8 (0.45) TLR8TLR7
SCHEMBL27078334 0.85 TLR8 (0.45) TLR8TLR7
SCHEMBL27078265 0.83 TLR8 (0.44) TLR8TLR7
SCHEMBL24699323 0.83 TLR8 (0.55) TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197899-A1 2-AMINO-4-CARBOXAMIDE-BENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF BOLT BIOTHERAPEUTICS, INC. (US) 2024-06-20 — — US disclosed
EP-4313161-A1 2-AMINO-4-CARBOXAMIDE-BENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF Bolt Biotherapeutics, Inc. (US) 2024-02-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197899-A1 2-AMINO-4-CARBOXAMIDE-BENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF AADAC, BRD4, IDO2 TLR8 3049/4885TLR7 1714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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