Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2449306 | 0.85 | MET (0.77) | METKCNH2 | |
| SCHEMBL2450025 | 0.80 | MET (0.83) | METKCNH2 | |
| SCHEMBL2450362 | 0.79 | MET (0.98) | METKCNH2 | |
| SCHEMBL2447759 | 0.79 | MET (0.69) | METKCNH2 | |
| SCHEMBL2445234 | 0.78 | MET (1.00) | METKCNH2 | |
| SCHEMBL2447015 | 0.77 | MET (0.75) | METKCNH2 | |
| SCHEMBL2445979 | 0.77 | MET (1.00) | METKCNH2 | |
| SCHEMBL2325612 | 0.77 | MET (1.00) | METKCNH2 | |
| SCHEMBL2450745 | 0.77 | MET (0.81) | METKCNH2 | |
| SCHEMBL2326077 | 0.77 | MET (1.00) | METKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896421-B1 | BENZOCYCLOHEPTAPYRIDINES AS INHIBITORS OF THE RECEPTOR TYROSINE KINASE MET | MERCK SHARP & DOHME (US) | 2011-09-14 | — | — | EP | claimed |