SCHEMBL24508243

SCHEMBL24508243

Cc1ccc2ccc3ccc(-c4ccccc4)cc3c2n1

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.48
RAB9A P51151 1/20 0.48
CCR5 P51681 1/20 0.48
METAP2 P50579 1/20 0.42
PLG P00747 1/20 0.41
PLAU P00749 1/20 0.41
ADORA1 P30542 2/20 0.41
TRIM58 Q8NG06 1/20 0.41
ADORA2A P29274 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032436 0.82 CCR1 (0.46) CCR1RAB9ACCR5METAP2
SCHEMBL10032418 0.80 PARP1 (0.45) RAB9APLGPLAUADORA1TRIM58
SCHEMBL10032345 0.80 PARP1 (0.45) RAB9APLGPLAUADORA1TRIM58
SCHEMBL19849763 0.78 ACVR1 (0.41) CCR1RAB9ACCR5METAP2
SCHEMBL10032321 0.77 PARP1 (0.43) RAB9APLGPLAU
SCHEMBL10032456 0.77 PARP1 (0.43) RAB9APLGPLAU
SCHEMBL31198218 0.77 PARP1 (0.43) RAB9APLGPLAU
SCHEMBL10032457 0.77 PARP1 (0.46) RAB9APLGPLAU
SCHEMBL10032361 0.77 PARP1 (0.43) RAB9APLGPLAU
SCHEMBL10032348 0.77 PARP1 (0.43) RAB9APLGPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022124502-A1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND LG Display Co.,Ltd. (KR) 2022-06-16 WO disclosed