SCHEMBL31198218

SCHEMBL31198218

c1ccc(-c2ccc3ccc4ccc(-c5cccc(-c6ccc7ccc8ccc(-c9ccccc9)cc8c7n6)c5)nc4c3c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.43
MEN1 O00255 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
PLG P00747 1/20 0.40
PLAU P00749 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
KMO O15229 2/20 0.38
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
BACE1 P56817 1/20 0.38
FGFR1 P11362 1/20 0.38
GP6 Q9HCN6 1/20 0.38
CDK4 P11802 1/20 0.37
CCND1 P24385 1/20 0.37
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032456 1.00 PARP1 (0.43) PARP1MEN1RAB9AKMT2APLG
SCHEMBL10032321 1.00 PARP1 (0.43) PARP1MEN1RAB9AKMT2APLG
SCHEMBL10032361 1.00 PARP1 (0.43) PARP1MEN1RAB9AKMT2APLG
SCHEMBL10032348 1.00 PARP1 (0.43) PARP1MEN1RAB9AKMT2APLG
SCHEMBL10032457 0.97 PARP1 (0.46) PARP1MEN1RAB9AKMT2APLG
SCHEMBL10032355 0.97 PARP1 (0.46) PARP1MEN1RAB9AKMT2APLG
SCHEMBL21674508 0.95 PARP1 (0.45) PARP1MEN1RAB9AKMT2APLG
SCHEMBL10032508 0.95 PARP1 (0.45) PARP1MEN1RAB9AKMT2APLG
SCHEMBL10032407 0.94 PARP1 (0.39) PARP1MEN1RAB9AKMT2APLG
SCHEMBL10032345 0.93 PARP1 (0.45) PARP1MEN1RAB9AKMT2APLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080750-A Light-emitting layer material with spiro structure, preparation method thereof and organic electroluminescent device 中国科学技术大学 2024-12-06 CN disclosed