Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30545126 | 1.00 | CRBN (0.39) | CRBNDDB1 | |
| SCHEMBL30543656 | 0.86 | DDB1 (0.36) | CRBNDDB1 | |
| SCHEMBL31211812 | 0.86 | DDB1 (0.40) | CRBNDDB1 | |
| SCHEMBL25338787 | 0.86 | DDB1 (0.36) | CRBNDDB1 | |
| SCHEMBL25337893 | 0.86 | DDB1 (0.40) | CRBNDDB1 | |
| SCHEMBL24508322 | 0.84 | DDB1 (0.48) | CRBNDDB1 | |
| SCHEMBL30545185 | 0.83 | MELK (0.37) | CRBNDDB1 | |
| SCHEMBL24509261 | 0.83 | MELK (0.37) | CRBNDDB1 | |
| SCHEMBL23832666 | 0.83 | CRBN (0.37) | CRBNDDB1 | |
| SCHEMBL30225582 | 0.83 | CRBN (0.37) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669722-A | Interleukin-1 receptor-related kinase (IRAK) degradants and uses thereof | 凯麦拉医疗公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2022125790-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |