Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3064191 | 0.70 | MTNR1A (0.65) | MTNR1AMTNR1BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL32670725 | 0.69 | TAAR1 (0.47) | MTNR1AMTNR1BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30360651 | 0.69 | TAAR1 (0.47) | MTNR1AMTNR1BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30360707 | 0.69 | TAAR1 (0.47) | MTNR1AMTNR1BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL19812780 | 0.69 | TAAR1 (0.47) | MTNR1AMTNR1BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL19821165 | 0.67 | MTNR1A (0.46) | MTNR1AMTNR1BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL23016564 | 0.65 | MTNR1A (0.47) | MTNR1AMTNR1BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL19813056 | 0.61 | TAAR1 (0.43) | MTNR1AMTNR1BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL19813086 | 0.61 | TAAR1 (0.43) | MTNR1AMTNR1BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL32670720 | 0.61 | TAAR1 (0.43) | MTNR1AMTNR1BCHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220185799-A1 | 1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2022-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185799-A1 | 1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS | CNR1, HCRTR1, CNR2 | MTNR1A 72/4885MTNR1B 62/4885TRPV1 2804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.