Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23568249 | 0.85 | CARM1 (0.34) | KDM1AKDM4EKMT2ATDP1HTR1A | |
| SCHEMBL22856133 | 0.85 | CARM1 (0.34) | KDM1AKDM4EKMT2ATDP1HTR1A | |
| SCHEMBL23696220 | 0.85 | PRMT6 (0.36) | KDM1AKDM4EKMT2ATDP1HTR1A | |
| SCHEMBL22837707 | 0.84 | KDM1A (0.32) | KDM1AKDM4EKMT2ATDP1HTR1A | |
| SCHEMBL22906363 | 0.84 | KDM1A (0.32) | KDM1AKDM4EKMT2ATDP1HTR1A | |
| SCHEMBL25727621 | 0.84 | KDM4E (0.32) | KDM4EKMT2ATDP1LMNA | |
| SCHEMBL23696201 | 0.84 | KDM4E (0.32) | KDM4EKMT2ATDP1LMNA | |
| SCHEMBL24508257 | 0.84 | CARM1 (0.34) | KDM1AHTR1AHTR7 | |
| SCHEMBL22837671 | 0.83 | SLC6A2 (0.33) | KDM1AKDM4EKMT2ATDP1HTR1A | |
| SCHEMBL23695901 | 0.83 | KDM1A (0.32) | KDM1AKDM4EKMT2ATDP1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125790-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |