SCHEMBL24510642

CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(C(C)(C)C)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)OC(C)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	CDYL2	Q8N8U2	6/20	0.68

▸	CBX7	O95931	4/20	0.68

▸	CBX8	Q9HC52	4/20	0.68

▸	CBX4	O00257	3/20	0.68

▸	CBX6	O95503	1/20	0.61

▸	CBX2	Q14781	1/20	0.61

▸	OPRK1	P41145	9/20	0.45

▸	OPRM1	P35372	3/20	0.45

▸	PRSS1	P07477	1/20	0.43

▸	PRSS2	P07478	1/20	0.43

▸	PRSS3	P35030	1/20	0.43

▸	KISS1R	Q969F8	1/20	0.43

▸	PSMB5	P28074	2/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29613457	0.92	CDYL2 (0.79)	CDYL2CBX7CBX8CBX4CBX6
SCHEMBL24510644	0.91	CDYL2 (0.72)	CDYL2CBX7CBX8CBX4CBX6
SCHEMBL29613443	0.91	CDYL2 (0.70)	CDYL2CBX7CBX8CBX4CBX6
SCHEMBL29129080	0.90	CDYL2 (0.70)	CDYL2CBX7CBX8CBX4CBX6
SCHEMBL29129077	0.90	CDYL2 (0.70)	CDYL2CBX7CBX8CBX4CBX6
SCHEMBL23717921	0.83	CDYL2 (0.87)	CDYL2CBX7CBX8CBX4CBX6
SCHEMBL23682719	0.83	CDYL2 (0.87)	CDYL2CBX7CBX8CBX4CBX6
SCHEMBL23718040	0.83	CDYL2 (0.87)	CDYL2CBX7CBX8CBX4CBX6
SCHEMBL23682865	0.83	CDYL2 (0.87)	CDYL2CBX7CBX8CBX4CBX6
SCHEMBL26219950	0.83	CDYL2 (0.87)	CDYL2CBX7CBX8CBX4CBX6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022126000-A1	METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1	Design Therapeutics, Inc. (US)	2022-06-16	—	—	WO	disclosed