Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14009997 | 0.88 | MMP2 (0.50) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL737926 | 0.88 | MMP2 (0.50) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL16171971 | 0.88 | MMP2 (0.50) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL14048310 | 0.87 | MMP2 (0.52) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL12727418 | 0.87 | MMP2 (0.52) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL20976930 | 0.87 | MMP2 (0.52) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL805209 | 0.87 | MMP2 (0.52) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL16203423 | 0.87 | MMP2 (0.52) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL22679775 | 0.86 | MMP2 (0.49) | MMP2MMP9MMP8CYP2A6CTSL | |
| SCHEMBL19203659 | 0.86 | MMP2 (0.49) | MMP2MMP9MMP8CYP2A6CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022123462-A1 | RADIOLABELLED PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITORS AND USE THEREOF | 3B PHARMACEUTICALS GMBH (DE) | 2022-06-16 | — | — | WO | disclosed |